ABSTRACT
Three viruses were isolated from different geographic regions of the Sharkia from cutaneous and ocular lesions in turkeys during natural outbreaks of pox disease which occurred in summer 2004, they were identified serologically as Avi-poxviruses, the isolates were studied for physico-chemical, biological characterization and the host spectrum to some of avian species. The evidence from the characterization of the viruses isolated and the experiments described here suggests that: [1] The pox viruses responsible for the outbreaks in turkey's flocks in Sharkia were essentially identical. [2] The results revealed a high degree of heterogeneity among the avian species; where the turkeys poxvirus inoculated turkeys had the highest lesioa, followed by chick'-as, pigeons and ducks respectively. [3] This study revealed marked crisis of the infection with turkey pox virus on other avian species